This dashboard is for HDX data for BF2-B15:01 and B2-B19:01 +/- peptide
This tab contains the mean uptake per timepoint overlaid onto the structures as animations.
The second tab shows the BF2*19:01 three state experiment that confirms the MHC can be re-loaded with peptide after cleavage.
The third tab has heatmaps comparing peptide free to peptide bound for each allotype, providing a measure of peptide dependent exchange.
The fourth and fifth tabs compare allotypes peptide free and peptide bound to give a measure of allotype dependent exchange using the mean HDX across overlapping peptides for each timepoint.
The sixth and seventh tabs show the HDX maps of the individual peptides. You may need to zoom in to see the peptides clearly.
The eighth tab shows HDX exchange rates for selected fragments using the mean of the mean uptake for that region as a percentage of maximum theoretical exhange.